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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Transfusion. 2018 Nov 26;59(1):67–78. doi: 10.1111/trf.14998

Table 3:

Multivariate linear modeling of hemolysis measures. Differences are considered significant at p<0.001. Reference values were 0 donations, no iron consumption, age < 21, Female, and White race-ethnicity. For continuous measures like ferritin there is no reference value.

Oxidative Hemolysis Osmotic Hemolysis Storage Hemolysis
beta p beta p beta p
Donation Frequency 1-4 −0.7988 0.0016 0.0998 0.7366 −0.008 0.2723
Donation Frequency 5-8 −0.8267 0.0159 −0.7796 0.0477 6.00E-04 0.9492
Donation Frequency 9+ −1.569 < 0.0001 −1.0589 0.0119 0.0222 0.0315
Ferritin 0.0071 < 0.0001 0.0098 < 0.0001 3.00E-04 < 0.0001
Iron Intake Yes −3.7556 < 0.0001 −1.1919 < 0.0001 −0.0032 0.5911
Age 21-25 0.9787 0.0535 −0.6215 0.3017 0.0237 0.1069
Age 25-30 0.4887 0.3216 −0.6827 0.2414 0.0051 0.7203
Age 30-35 1.0576 0.0361 −0.2312 0.6981 0.0164 0.2608
Age 35-40 1.0243 0.0475 0.3122 0.6105 0.046 0.0021
Age 40-45 1.5454 0.0026 0.285 0.6422 0.0253 0.0917
Age 45-50 0.7283 0.1516 0.9106 0.1282 0.0386 0.0084
Age 50-55 −0.4248 0.3823 0.2013 0.7267 0.0417 0.003
Age 55-60 −1.4726 0.0023 0.3644 0.5223 0.0456 0.0011
Age 60-65 −2.3678 < 0.0001 0.1337 0.8218 0.0261 0.072
Age >= 65 −3.3611 < 0.0001 −0.2263 0.6964 0.0564 < 0.0001
Race African American −0.0816 0.783 −13.028 < 0.0001 0.021 0.0176
Race Asian −0.3059 0.3513 −3.2147 < 0.0001 0.0579 < 0.0001
Race Hispanic 0.74 0.0453 −1.228 0.0051 0.0535 < 0.0001
Sex M 1.0175 < 0.0001 4.1337 < 0.0001 0.0435 < 0.0001