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VGB treatment significantly decreased spontaneous activity while increasing driven rates. For the mid- and high-frequency tonotopic regions, spontaneous activity (A) was significantly decreased (****p < 0.0001, *p < 0.05) following VGB treatment. The maximum tone-evoked spike rates (B) showed significant increases for all frequencies following treatment (****p < 0.0001). Abbreviation: VGB, vigabatrin.
