Table 4.
Calcium cycling gene expressions in skeletal muscle at 1 mo (baseline) and after 5 mo of CRT device implantation
| 1M | 5M | |
|---|---|---|
| L-type Ca2+ channel | ||
| NoET | 1.6 ± 1.0 | 0.3 ± 0.1 |
| ET | 0.6 ± 0.5 | 4.4 ± 2.6 |
| NCX relative expression | ||
| NoET | 3.2 ± 1.2 | 0.9 ± 0.3 |
| ET | 1.2 ± 0.5 | 8.3 ± 2.4* |
| Phospholamban relative expression | ||
| NoET | 1.1 ± 0.5 | 0.3 ± 0.2 |
| ET | 0.2 ± 0.1 | 6.4 ± 2.5 |
| Ryanodine relative expression | ||
| NoET | 4.3 ± 1.1 | 0.9 ± 0.5* |
| ET | 2.9 ± 0.8 | 3.7 ± 1.1 |
| Serca 1 relative expression | ||
| NoET | 2.2 ± 1.3 | 0.7 ± 0.2 |
| ET | 0.9 ± 0.4 | 3.4 ± 0.8 |
| Serca 2 relative expression | ||
| NoET | 1.3 ± 0.5 | 0.5 ± 0.3 |
| ET | 2.4 ± 0.9 | 5.6 ± 1.9 |
Values are means ± SE. NCX, Na+-Ca2+ exchanger.
*
P < 0.05 within-group comparison.