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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Gastroenterology. 2018 Jul 17;155(5):1495–1507.e15. doi: 10.1053/j.gastro.2018.07.014

Figure 5.

Figure 5

Valerate inhibits C difficile vegetative growth in batch cultures. Vegetative cells were inoculated into supplemented brain heart infusion broth containing varying concentrations of valerate (0, 1, 2, 3, 4, 5, 10, and 20 mM) and OD600 measurements were taken at 0, 2, 4, 6, and 8 hours. The change in OD600 (from a time point during the exponential phase) was plotted against the concentrations of valerate tested. (A) C difficile ribotype 010, (B) C difficile ribotype 012, (C) C difficile ribotype 027, (D) B. uniformis, (E) B. vulgatus, (F) C. scindens. Error bars represent the mean ± standard deviation, * p<0.05, ** p<0.01, *** p<0.001.