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Schematic diagram of selected low-density lipoprotein receptor family members. The domain configurations and relative sizes of LRP1, LRP2, LRP4, LRP5/6, and LRP8 are shown. Each commonly shared domain is indicated within the structure by symbols shown in the box at the top right. The COOH terminus of the protein is on the cytoplasmic side of the membrane, and the NH2 terminus is extracellular.
