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LRP4 facilitates presentation of sclerostin to LRP5/6. LRP4 and LRP5/6 are shown with the same domain symbols as in FIGURE 1. Sclerostin is shown in yellow. The COOH termini of LRP4 and LRP5/6 are on the cytoplasmic side of the plasma membrane; the NH2 termini are extracellular.
