Table 4. Multivariable Odds Ratio for gout among patients with CKD in the Irish health system.
Variable | AOR (95% CI) | P-value | AOR (95% CI) | P-value |
---|---|---|---|---|
Model 1 (N = 286) | Model 2 (N = 126) | |||
Age per 5 year increase | 1.09 (0.96–1.24) | 0.185 | 1.00 (0.82–1.21) | 0.962 |
Male vs Female | 1.95 (0.95–4.03) | 0.070 | 2.99 (0.79–11.33) | 0.107 |
Coronary Heart Disease | 1.57 (0.68–3.63) | 0.291 | 1.47 (0.37–5.76) | 0.583 |
Diuretic use | 1.79 (0.87–3.68) | 0.111 | 0.78 (0.20–2.95) | 0.710 |
eGFR per 5 ml/min/1/73m2 decrease | 1.11 (1.01–1.22) | 0.037 | 1.03 (0.85–1.23) | 0.792 |
Serum albumin per 1 g/L decrease | 1.09 (1.02–1.16) | 0.008 | 1.15 (1.01–1.30) | 0.040 |
Serum phosphate per 1 mmol/l increase | 0.34 (0.08–1.46) | 0.147 | 0.40 (0.04–4.20) | 0.445 |
Parathyroid hormone per 50 pg/mL increase | – | 1.38 (1.08–1.77) | 0.011 |
Model 1: adjusted for continuous variables (age, eGFR, serum albumin, serum phosphate) and categorical variables (sex, history of coronary heart disease and diuretic use). The model had a C-statistic 0.77 and there was no evidence of poor fit from the Hosmer and Lemeshow goodness of fit test (p = 0.6). Model 2: adjusted for all variables as Model 1 in addition to serum parathyroid hormone (PTH). This model had a C-statistic of 0.83 and there was no evidence of poor fit from the Hosmer and Lemeshow goodness of fit test (p = 0.9).