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. 2019 Jan 25;14(1):e0210487. doi: 10.1371/journal.pone.0210487

Table 4. Multivariable Odds Ratio for gout among patients with CKD in the Irish health system.

Variable AOR (95% CI) P-value AOR (95% CI) P-value
Model 1 (N = 286) Model 2 (N = 126)
Age per 5 year increase 1.09 (0.96–1.24) 0.185 1.00 (0.82–1.21) 0.962
Male vs Female 1.95 (0.95–4.03) 0.070 2.99 (0.79–11.33) 0.107
Coronary Heart Disease 1.57 (0.68–3.63) 0.291 1.47 (0.37–5.76) 0.583
Diuretic use 1.79 (0.87–3.68) 0.111 0.78 (0.20–2.95) 0.710
eGFR per 5 ml/min/1/73m2 decrease 1.11 (1.01–1.22) 0.037 1.03 (0.85–1.23) 0.792
Serum albumin per 1 g/L decrease 1.09 (1.02–1.16) 0.008 1.15 (1.01–1.30) 0.040
Serum phosphate per 1 mmol/l increase 0.34 (0.08–1.46) 0.147 0.40 (0.04–4.20) 0.445
Parathyroid hormone per 50 pg/mL increase 1.38 (1.08–1.77) 0.011

Model 1: adjusted for continuous variables (age, eGFR, serum albumin, serum phosphate) and categorical variables (sex, history of coronary heart disease and diuretic use). The model had a C-statistic 0.77 and there was no evidence of poor fit from the Hosmer and Lemeshow goodness of fit test (p = 0.6). Model 2: adjusted for all variables as Model 1 in addition to serum parathyroid hormone (PTH). This model had a C-statistic of 0.83 and there was no evidence of poor fit from the Hosmer and Lemeshow goodness of fit test (p = 0.9).