Fig 2. Infarct volumes at day 21 following various cell transplantation timings (Protocol 1).

There was a significant difference (*P<0.05, Kruskal-Wallis test) in infarct volume between the PBS injection and RAC injection groups at day 1, whereas PB-MNC had no effect (A) (PBS: n = 13, MNCs: n = 12, RACs: n = 13). Similar findings were observed in animals transplanted at day 3, showing a significant effect of RAC injection but not of MNC injection, compared to the PBS control group (B) (PBS: n = 8, MNCs: n = 8, RACs: n = 7). There was no difference in infarct volume between PBS and RACs (1 x 10⁴ /50 μL) in the case of cell transplantation at day 5 (C) (each group: n = 5) or at day 7 (D) (each group: n = 5) after MCAO.