Fig 1. Bone formation at periosteal surface is affected by genotype and exercise during growth.
A) Representative image of the new tissue identified at the endosteal and periosteal surfaces, along with the pre-existing tissue in-between (bar = 500 μm). The area of tissue between florescent labels was used to quantify B) new endosteal tissue, C) pre-existing tissue, and D) new periosteal tissue. Main effects are noted for genotype (G), physical activity (A), and their interaction (GxA). Individual differences with a p<0.05 were found when compared to sedentary-PPRfl/fl (‡), and exercised-PPRfl/fl (*). Mean ± stdev (n = 10). D).