Table 2. The enrichment data for gut hormone receptors.

Receptor	Template / Binding site / Model number	BEDROC(alpha = 20)	ROC	AUC	EF1%	EF5%	EF10%
GLP1R	5VEW—allosteric
	Model 1	0.589	0.94	0.94	29	14	7
	Model 2	0.559	0.98	0.97	38	10	8
	5VEW—orthosteric
	Model 1	0.423	0.93	0.92	0	12	6
	Model 2	0.330	0.93	0.92	9.6	6.1	5
GIPR	4L6R –orthosteric
	Model 1	0.773	0.94	0.93	50	18	8.9
	Model 2	0.668	0.95	0.95	40	14	7
	4L6R –allosteric
	Model 1	0.453	0.94	0.94	10	12	8.9
	Model 2	0.518	0.92	0.91	30	10	7
GCGR	5XEZ—orthosteric
	Model 1	0.741	0.91	0.91	43	16	8
	Model 2	0.440	0.89	0.89	11	10	6
	5XEZ—allosteric
	Model 1	0.441	0.90	0.89	0	12	8
	Model 2	0.419	0.89	0.88	11	10	7
Results for corresponding X-ray structures
Receptor	PDB id / Binding site	BEDROC(alpha = 20)	ROC	AUC	EF1%	EF5%	EF10%
GLP1R	5VEW—orthosteric	0.441	0.90	0.90	9.6	10	7
	5VEW—allosteric	0.278	0.87	0.87	0	6.1	6
GCGR	5XEZ—orthosteric	0.197	0.77	0.77	0	4	4
	5XEZ—allosteric	0.678	0.92	0.91	43	14	8