Table 1. Comparison of studies using non pharmacological pre or post treatment strategies in LPS induced sepsis in mice.

Author	Year	Species	Dose of LPS	Pre or Post Treatment	Mode	24 hr Survival	48 hr Survival
Ishizashi et al(28)	1995	5 week old C57BL/6J	IV LPS 20mg/kg	Pre-Treated (P. acnes, IP 7 days before exercise). Exercise 120 min prior to LPS	Voluntary Wheel Running	Control = 0 Exerc = 22%
Martin et al (27)	2013	22 month C57BL/6J	Max Dose IP 0.33mg/kg	Pre treatment 10 weeks	Voluntary wheel running	Control = 73% Exerc = 100%
Kim et al (29)	2014	6 weeks mice BALB/c	IP 20 mg/kg	Remote Ischemic Pre (RIPC) & Post Conditioning (RpostC), immediately before or after LPS	Hind-limb tourniquet 3 cycles (10min Ischemia/10min reperfusion)	Control = 80% RIPC = 100% RpostC = 90%	Control = 15% RIPC = 65% Rpostc = 65%
Irahara et al (26)	2016	11 weeks C57BL/6J	Max Dose IP 10mg/kg	Post Treatment exercise	Treadmill 30 min X 3 after LPS and 30 min X 2 next day	Control = 80% Exercise = 100%	Control = 60% Exercise = 100%
Adams et al Current work	2018	6–10 weeks C57BL/6J	IP 40mg/kg	Pre and Post Treatment	pGz Pre Treatment = 3 days Post Treatment = 30 min after LPS	Control = 6% pGz-LPS = 75% LPS-pGz = 100%	LPS-Control = 0% pGz-LPS = 61% LPS-pGz = 83%

Compendium of mice studies using non pharmacological interventions pre or post treatment in models of LPS induced endotoxin in mice published from 1995 to 2018 with at least 24 hrs. survival. Each study shows the dose of LPS, method of administration (IP = intraperitoneal, IV = intravenous) the pre or post treatment strategy, the modality and 24 and 48 hrs. survival.