Fig 9. Cumulative health index rank in young control (Y-CON), old sedentary (O-SED), and lifelong aerobically trained (O-AET) C57BL/J6 mice.
Common predictors of independence and health- and lifespan, including existing morbidities, aerobic capacity, skeletal muscle mass, muscle strength and endurance, and motor coordination were individually ranked on a 5-grade scale (see Methods), averaged and presented as a cumulative health index, and evaluated by Kruskal Wallis and Dunn’s multiple comparison tests. Group means that are statistically different from each other do not share the same alphabetical letter (P < 0.05).