Fig 2. Four distinct assumptions about heterogeneous DENV exposure.

Scenario A represents homogeneous transmission of DENV ignoring mosquitoes and human movement patterns, leading to everyone experiencing the same hazard of exposure to any serotype of DENV. In scenarios B, C, and D, DENV is transmitted by mosquitoes, and human and mosquito movement patterns are considered. Scenario B represents homogeneous attractiveness of different humans to mosquitoes at a given location. Scenario C represents human attractiveness to mosquitoes proportional to human body size. Scenario D represents heterogeneous human attractiveness to mosquitoes based on a gamma distribution with shape 1.43 and scale 1, regardless of their body size.