Table 3. Enriched pathways: results using the DIANA-mirPath v3.0 software.
KEGG pathway maps | Enriched pathways | Adjusted P-valuesa |
---|---|---|
Metabolism | ||
Lipid metabolism | Fatty acid biosynthesis (hsa00061) | <1x10-325 |
Fatty acid metabolism (hsa01212) | <1x10-325 | |
Environmental Information Processing | ||
Signaling molecules and interaction | ECM-receptor interaction (hsa04512) | <1x10-325 |
Signal transduction | TGF-beta signaling pathway (hsa04350) | <1x10-325 |
Hippo signaling pathway (hsa04390) | <1x10-325 | |
FoxO signaling pathway (hsa04068) | 4,88x10-13 | |
PI3K-Akt signaling pathway (hsa04151) | 0,0006 | |
mTOR signaling pathway (hsa04150) | 0,0008 | |
Cellular processes | ||
Cell growth and death | p53 signaling pathway (hsa04115) | <1x10-325 |
Cell cycle (hsa04110) | 5,32x10-13 | |
Cellular community | Adherens junction (hsa04520) | 9,21x10-15 |
Focal adhesion (hsa04510) | 1,34x10-6 | |
Human Diseases | ||
Cancers: overview | Pathways in cancer (hsa05200) | <1x10-325 |
Proteoglycans in cancer (hsa05205) | <1x10-325 | |
Transcriptional misregulation in cancer (hsa05202) | 0,019 |
aAdjusted P- values were obtained by using the Benjamini–Hochberg method.