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. Author manuscript; available in PMC: 2020 Jan 10.
Published in final edited form as: Cell. 2019 Jan 10;176(1-2):11–42. doi: 10.1016/j.cell.2018.09.048

Figure 3. Diverse biological functions of autophagy genes contribute to their roles in the regulation of mammalian disease.

Figure 3.

Shown are the major known biological functions of ATG genes and the broad categories of diseases that they regulate as predicted based on mouse experimental data and human genetic associations. Below major disease categories, some representative specific diseases are noted. Many other examples exist but are not shown due to space limitations.