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. 2019 Jan 25;14(1):e0211433. doi: 10.1371/journal.pone.0211433

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© 2019 Ivic et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — Vasomotor effect of cumulative dose-dependent administration of: PACAP1-38 (a), PACAP1-27 (b) and VIP (c) in carotid artery; and PACAP1-38 (d), PACAP1-27 (e) and VIP (f) in femoral artery of wild type (WT) and PACAP knockout (KO) mice in the presence of PAC1R antagonist M65. Arterial relaxation is marked as negative change in force. Data are expressed as means ± SEM (n = 3-6/group). *p < 0.05 WT vs. WT+M65 mice; ^#p < 0.05 KO vs. KO+M65 mice; ^Δp < 0.05 WT+M65 vs. baseline; ^$p < 0.05 KO+M65 vs. baseline.