Table 2:
Phthalate Metabolite | T11 | T32 | T1 T3 Spearman Correlation7 | ||||
---|---|---|---|---|---|---|---|
N | %>LOD3 | GM4 (GSD)5,6 | N | %>LOD | GM (GSD) | ||
Mono-isobutyl phthalate (MIBP) | 668 | 99 | 5.2 (2.4) | 679 | 95 | 7.2 (2.6) | 0.40 |
Monoethy 1 phthalate (MEP) | 668 | 100 | 37.6 (3.8) | 679 | 98 | 42.1 (4.5) | 0.40 |
Mono-n-butyl phthalate (MNBP) | 668 | 95 | 8.3 (2.4) | 679 | 98 | 9.7 (2.7) | 0.27 |
Mono-benzyl phthalate (MBZP) | 668 | 95 | 4.3 (2.9) | 679 | 95 | 4.8 (3.2) | 0.46 |
Mono-carboxy-iso-nonyl phthalate (MCNP) | 406 | 96 | 2.7 (2.8) | 679 | 98 | 2.8 (2.7) | 0.15 |
Mono-carboxy-iso-octyl phthalate (MCOP) | 406 | 100 | 19.3 (3.5) | 679 | 100 | 16.0 (3.3) | 0.27 |
Mono-(3-carboxypr opyl) phthalate (MCPP) | 668 | 94 | 2.5 (3.6) | 679 | 87 | 2.4 (3.7) | 0.20 |
Mono-(2-ethylhexyl) phthalate (MEHP) | 668 | 70 | 2.5 (2.5) | 679 | 76 | 2.1 (2.4) | 0.14 |
Mono-(2-ethyl-5-hydroxyh exyl) phthalate (MEHHP) | 668 | 100 | 7.9 (2.6) | 679 | 99 | 6.7 (2.5) | 0.12 |
Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) | 668 | 99 | 5.5 (2.5) | 679 | 100 | 5.3 (2.5) | 0.13 |
Mono-(2-ethyl-5-carboxype ntyl) phthalate (MECPP) | 668 | 100 | 10.6 (2.4) | 679 | 100 | 12.2 (2.3) | 0.20 |
∑Di-2-ethylhexyl phthalate (DEHP) | 668 | N/A | 93.4 (2.3) | 679 | N/A | 47.7 (2.4) | 0.11 |
T1 = First trimester
T3 = Third trimester
LOD = Limit of detection
GM = Geometric mean
GSD = Geometric standard deviation
Units are μg/Lfor all individual phthalates; nmol/mL for ∑DEHP
Within-woman, between-trimester correlations on SG-adjusted phthalates