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. 2019 Feb 1;186:286–300. doi: 10.1016/j.neuroimage.2018.11.006

Table 3.

Comparison of the effects of FIX denoising on t-statistics from the GLM output and significantly active voxel counts for all 15 subjects. T-statistics: using FIX denoising resulted in an increase in the mean t-statistic in all grey matter ROIs (maximum t-statistic in parentheses). * = ROIs in which FIX denoising resulted in statistically significant increases in t-statistics (voxel-based thresholding, 5% FWER corrected). # active voxels: using FIX denoising also resulted in an increase in the number of significantly active voxels using all three thresholding approaches. Voxel is FDR corrected; cluster and TFCE are FWER corrected. ACC = anterior cingulate cortex; PoCG = postcentral gyrus; TFCE = threshold free cluster enhancement.

No FIX With FIX
T-statistics ACC 2.065 (4.822) 2.104 (4.030)
Insula 2.199 (4.839) 2.977* (5.224)
PoCG 2.249 (5.329) 2.959* (6.987)
Thalamus 1.527 (7.387) 2.565* (6.797)



# active voxels Voxel 0 66,984
Cluster 30,837 82,837
TFCE 1311 66,756