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. 2019 Jan 25;10(2):74. doi: 10.1038/s41419-019-1328-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a FACS analysis of control, KO, WT SETD3 rescue and catalytic inactive (Y313A) SETD3 rescue cells, post DOX or vehicle treatment. b Quantification of apoptotic cells percentage of three-independent FACS analyses, ***p ≤ 0.001, ns p > 0.05. Western blot of the control, KO and rescued cells lysate. c SETD3 KO and rescued (with WT or Y313A) cells were stained with FITC-Annexin V and PI post treatment with DOX and viewed under fluorescent microscope (scale bar signifies 100 µM, pictures were taken under ×20 magnification)