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. 2019 Jan 25;10(2):68. doi: 10.1038/s41419-019-1305-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a Immunohistochemical detection of KDM4B and p-c-Jun in gastric tissue specimens. The expression level of KDM4B and the signal of p-c-Jun in gastric tissue specimens are elevated in the cancerous site as compared with the adjacent normal site. b The correlation between KDM4B expression and p-c-Jun signal in 87 gastric cancer biopsies. Statistical significance was evaluated using the Chi-square test. c Overall survival of GC patients with co-expression of KDM4B and p-c-Jun in advanced gastric cancer biopsies defined by the Kaplan–Meier curves. Overall survival of patients with advanced T stage (T2−T4; n = 67) were assessed. +, positive expression in both KDM4B and p-c-Jun; –, negative expression in one of KDM4B and p-c-Jun or none. d Kaplan–Meier survival curves. KM plots of gastric cancer survival for patients with KDM4B and IL-8 expression