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(A) Subapical Dlish is increased in wing disc epithelium cells homozygous for fat null mutation (7, 8). (Magnification: 2,400×.) (B) Model of inputs from the Fat, Ds, and Crumbs ICDs into the Hippo growth control pathway; based on this work and others (1, 2, 33). Studies differ on whether Fbxl7 regulates Dachs via ubiquitination (17, 18). Mnb, minibrain; Riq, riquiqui; ub, ubiquitination.
