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. 2019 Jan 25;10:46. doi: 10.1186/s13287-019-1136-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Changes in ovarian function and histology after hAD-MSC-CM injection. a The percentage of rats with abnormal estrous cycles was observed at 2, 4, and 8 weeks after CM injection. b–d Serum levels of AMH (b), FSH (c), and E2 (d) were evaluated at 0, 2, 4, and 8 weeks after CM injection. e, f Changes in the histology of ovaries were analyzed using HE staining (e × 40), and the number of follicles at different stages was counted and compared (f) in the three groups at 4 weeks after CM injection. *P < 0.05 and **P < 0.01. Scale bars, 100 μm