Fig. 2.

B. pilosicoli infection is associated with major systemic metabolism modifications. a Scores (right panel) and loadings (left panel) plots of the O-PLS-DA model calculated using 1D-NMR spectra of birds’ liver at PM1 as a matrix of independent variables and infection as a predictor infected birds (red square) and uninfected birds (blue circle). Loading plots shape represent the mean standard deviation of all NMR spectra acquired for the given model and multiplied by the O-PLS DA model weight that allow to visualize if metabolites are positively associated with infection (pointing downwards) or negatively (pointing upwards). The color scale represent the level of correlation between each data point and infection. b Same for the spleen. c same for the kidney. d same for the plasma. e same for the plasma at T1