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. 2019 Jan 25;9(1):e023334. doi: 10.1136/bmjopen-2018-023334

Table 4.

Rate of local lymph node metastasis in patients with crPTC and mPTC from 2008 to 2013

Period 94–95 96–97 98–99 00–01 02–03 04–05 06–07 08–09 10–11 12–13 14–15 Total P for difference P for trend
crPTC, n (%) 3 (23.1) 5 (33.3) 6 (50.0) 19 (59.4) 17 (41.5) 24 (27.6) 35 (29.7) 73 (30.7) 130 (34.7) 243 (34.9) 330 (22.2) 885 (28.4) <0.001 <0.001
mPTC, n (%) 2 (100) 0 (0) 1 (20.0) 3 (42.9) 0 (0) 3 (15.0) 20 (29.9) 23 (16.0) 62 (15.8) 129 (19.0) 84 (15.6) 327 (17.5) 0.005 0.087
P value 0.032 0.331 0.252 0.425 0.017 0.243 0.978 0.001 0.000 0.000 0.001

crPTC, clinical relevant papillary thyroid carcinoma; mPTC, micropapillary thyroid carcinoma.