Figure 2.

Effect of BMMSCs-conditioned medium and TGF-β1 on collagen I, III and α-SMA mRNA expression. Subconfluent serum starved cells were treated with either TGF- β1 (10ng/ml) or BM-derived MSCs conditioned medium for 48 hours. qRT-PCR for A) Col1a, B) Col 3a and C) α-SMA mRNA expression in MRC-5 cells showed increased production of collagen I, III and α-SMA when compared with control group. BM: bone marrow CM: conditioned medium, TGF-β1, transforming growth factor-β1, α-SMA: Alpha smooth muscle actin.