Table 3.
Myocardial SPECT Imaging Results Versus Exercise Capacity in Patients Achieving ≥85% of Their MAPHR.
| Characteristic | <7 METS* Achieved (n= 93) |
7-9 METS Achieved (n= 192) |
≥10 METS Achieved (n= 97) |
P-value |
|---|---|---|---|---|
| Perfusion | ||||
| Fixed Perfusion Defects† | 27 (29.0) | 30 (15.6) | 12 (12.4) | 0.005δ |
| Any Reversible Ischemia | 32 (34.4) | 42 (21.9) | 13 (13.4) | 0.002 |
| Percentage LV Ischemia (mean ± SD) | 2.7±5.2 | 1.7±4.3 | 0.9±3.1 | |
| LV Ischemic burden | 0.037 | |||
| 0% Ischemic | 61 (65.6) | 150 (78.1) | 84 (86.6) | |
| 1-4% Ischemic | 13 (14.0) | 18 (9.4) | 7 (7.2) | |
| 5-9% Ischemic | 8 (8.6) | 13 (6.8) | 3 (3.1) | |
| ≥10% Ischemic | 11 (11.8) | 11 (5.7) | 3 (3.1) | |
| Volumes & Function | ||||
| ESVI* (median (25th, 75th percentiles) | 12 (9, 20) | 11 (8, 17) | 15 (11, 19) | 0.07 |
| ESVI ≥25 | 14 (15.2) | 19 (10.1) | 12 (12.5) | 0.45 |
| EDVI* | 45 (38, 55) | 43 (38, 51) | 46 (39, 56) | 0.053 |
| Ejection fraction | 65 (57, 69) | 65 (59, 71) | 63 (58, 68) | 0.07 |
*
EDVI=end-diastolic volume index; ESVI=end-systolic volume index; METS=metabolic equivalents.
†
All fixed perfusion defects had either known prior infarction in the affected territory or an associated wall-motion abnormality.
δ
P-values are two-tailed with values <0.05 considered statistically-significant.