Table 4.
Univariable | Multivariable | |||||
---|---|---|---|---|---|---|
Predictors | X2 | Hazard Ratio (95% CI)* |
p-value | X2 | Hazard Ratio (95% CI) | p-value |
LVEF (5% decrements)* | 53.4 | 1.76 (1.51-2.04) | <0.001† | 37.1 | 1.68 (1.42-1.99) | <0.001 |
Male gender | 25.6 | 6.6 (3.17-13.56) | <0.001† | 12.6 | 4.54 (1.97-10.47) | <0.001 |
<10 METS achieved | 6.3 | 2.27 (1.19-4.30) | 0.012† | 12.5 | 3.76 (1.80-7.84) | <0.001 |
ST-Depression ≥1mm | 8.0 | 2.21 (1.28-3.81) | 0.005† | 6.9 | 2.42 (1.25-4.68) | 0.009 |
Known CAD* | 21.7 | 3.22 (1.97-5.29) | <0.001† | 4.2 | 1.84 (1.02-3.31) | 0.041 |
Prior MI* | 21.7 | 3.74 (2.15-6.53) | <0.001† | |||
Prior revascularization | 20.5 | 3.14 (1.92-5.16) | <0.001† | |||
Hypertension | 6.8 | 2.25 (1.22-4.12) | 0.009† | |||
Age (5-year increments) | 2.9 | 1.24 (0.97-1.58) | 0.086 | |||
Hyperlipidemia | 0.8 | 1.28 (0.75-2.19) | 0.37 | |||
Chest pain | 0.6 | 0.83 (0.51-1.34) | 0.44 | |||
Body mass index ≥30 | 0.5 | 0.78 (0.40-1.55) | 0.48 | |||
Diabetes mellitus | 0.4 | 1.22 (0.66-2.25) | 0.53 | |||
Tobacco use | 0.0 | 1.05 (0.60-1.82) | 0.87 |
CAD=coronary artery disease; CI=confidence interval; LVEF=left ventricular ejection fraction; METS=metabolic equivalents; MI=myocardial infarction.
P-values are two-tailed with values <0.05 considered statistically-significant.