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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Ophthalmology. 2018 Sep 27;126(2):283–295. doi: 10.1016/j.ophtha.2018.08.021

Table 5.

Change in best-corrected visual acuity (based on standard letters) at each visit by treatment group.

Change from Baseline within Treatment Group*
Estimate (95% Confidence interval) P-value
Periocular Intravitreal Dexamethasone
Week 4 2.78 (0.20, 5.36) 0.034 10.14 (7.59, 12.69) <0.0001 7.28 (4.45, 10.10) <0.0001
Week 8 4.37 (1.86, 6.89) 0.0007 9.70 (7.26, 12.13) <0.0001 9.53 (7.01, 12.05) <0.0001
Week 12 4.67 (2.14, 7.21) 0.0003 10.43 (7.67, 13.18) <0.0001 7.24 (4.34, 10.14) <0.0001
Week 20 5.17 (1.89, 8.46) 0.002 9.88 (6.72, 13.04) <0.0001 7.67 (5.23, 10.11) <0.0001
Week 24 4.07 (0.64, 7.51) 0.020 9.60 (6.87, 12.34) <0.0001 9.21 (6.62, 11.80) <0.0001

Difference in Change from Baseline between Treatment Groups*
Estimate (95% Confidence interval) P-value
Intravitreal - Periocular Dexamethasone - Periocular Dexamethasone Intravitreal
Week 4 7.36 (3.74, 10.98) <0.0001 4.49 (0.67, 8.31) 0.021 −2.86 (−6.66, 0.94) 0.14
Week 8 5.32 (1.82, 8.82) 0.003 5.16 (1.60, 8.72) 0.004 ࢤ0.16 (−3.67, 3.34) 0.93
Week 12 5.75 (2.01, 9.49) 0.003 2.57 (−1.28, 6.42) 0.19 ࢤ3.19 (−7.19, 0.81) 0.12
Week 20 4.71 (0.16, 9.26) 0.042 2.50 (−1.59, 6.58) 0.23 ࢤ2.21 (−6.20, 1.78) 0.28
Week 24 5.53 (1.14, 9.92) 0.013 5.14 (0.84, 9.44) 0.019 ࢤ0.40 (−4.16, 3.37) 0.84
*

An improvement of 15 letters (3 lines) corresponds to halving of the visual angle.