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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Pharmacol Ther. 2018 Oct 3;194:222–254. doi: 10.1016/j.pharmthera.2018.10.002

Figure 10.

Figure 10.

Structures of nicotinic receptor antagonists selective for α5-nAChR and α5-D398N-nAChR. A. AK-968/12117231: 1-(5-bromo-2-furoyl)-4-(4-fluorophenyl)piperazine B. AN-038/15563010: allyl 2-[(5-bromo-2-furoyl)amino]-3-phenylacrylate C. AE-641/30177001: N,N,4-trimethyl-5,6-diphenyl-1-hexanamine D. AK-968/40218701: 1-decyl-1-(2-undecynyl)piperidium