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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Pharmacol Ther. 2018 Oct 3;194:222–254. doi: 10.1016/j.pharmthera.2018.10.002

Table 5.

Growth-suppressive activity of VAChT inhibitor vesamicol in human lung cancer cell lines and athymic mouse models

Cell Line Nature of lung

cells
Growth-

inhibitory

Activity of

Vesamicol
Model used References
H82 Small cell lung

cancer
+ Cell culture 300, 306
A549 Lung

adenocarcinoma
+ Cell culture,

athymic mice
171
H1975, H838

H358
Lung

adenocarcinoma
+ Cell culture 53, 54, 171