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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Pharmacol Ther. 2018 Oct 3;194:222–254. doi: 10.1016/j.pharmthera.2018.10.002

Table 6.

The expression of choline transporters in normal human bronchial epithelial cells and lung cancer cell lines

Cell Line Nature of lung

cells
ChT1 CTL1-

5
OCT1-2 OCTN1 References
NHBE Normal human

bronchial

epithelium
+ 53, 54
SAEC Small airway

epithelial cells
+ 53, 54
HPAEpics Human

pulmonary

alveolar

epithelial cells
+ 171
H146,

H417,

H82
Small cell lung

cancer
+ 297
H69,

H345
Small cell lung

cancer
+ + 136, 297
H592 Small cell lung

cancer
CTL1-

3,

CTL5
297
H1694 Small cell lung

cancer
+ 297
H520,

H226
Squamous cell

carcinoma of

the lung
+ 53, 54, 171
H1703 Squamous cell

carcinoma of

the lung
OCT1,

OCT2
214
H1975,

H1563,

H1734,

H1650,

H23,

H650,

H358
Lung

adenocarcinoma
+ 53, 54, 171
H838 Lung

adenocarcinoma
+ OCT1,

OCT2
53, 54
A549 Lung

adenocarcinoma
+ CTL1 OCT1 OCTN1,

OCTN2
171, 335
H460 Lung

adenocarcinoma
OCT1,

OCT2
214
SPC-A-1,

H1299
Lung

adenocarcinoma
CTL1 OCTN1,

OCTN2
335
H441 Lung

adenocarcinoma
OCT1,

OCT2
OCTN1,

OCTN2
273

Blanks indicate Not Determined (ND)