Table 4. The ratios of growth inhibition (IR) for tumor volume (IRV) and tumor weight (IRW) of SW620 and SW620/Ad300 xenograft tumors at the end of the 15-day treatment period.

	SW620 tumors	SW620 tumors	SW620/Ad300 tumors	SW620/Ad300 tumors
	IRV^a(%)	IRW^b(%)	IRV^a(%)	IRW^b(%)
IPI-549	17	27	24	17
Paclitaxel	58^*	68^*	42	37
Combination	71^*	69^*	74^*^#	72^*^#

^a.

IRV and IRW are calculated as compared with the vehicle-only control group as described in the Materials and Methods section.

^b.

IRV and IRW are calculated as compared with the vehicle-only control group as described in the Materials and Methods section.

Significant (P < 0.05) as compared with vehicle-only group

Significant (P < 0.05) as compared with paclitaxel-only group