Table 2. Allele frequencies in cases and controls and odds ratio estimates for steroid-induced ONFH.
Alleles | MAF | pvalue for HWE | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
SNP-ID | Gene | Position | Aa/B | Case | Control | Case | Control | ORs | 95% CI | p | |
rs99365 | TIMP4 | 12152585 | T/C | 0.216 | 0.274 | 0.488 | 1 | 0.73 | 0.559 | 0.954 | 0.02a |
rs17035945 | TIMP4 | 12153128 | T/C | 0.139 | 0.155 | 0.803 | 0.514 | 0.87 | 0.634 | 1.207 | 0.42 |
rs308952 | TIMP4 | 12154122 | A/G | 0.219 | 0.274 | 1 | 1 | 0.75 | 0.571 | 0.973 | 0.03a |
rs3817004 | TIMP4 | 12154174 | G/A | 0.222 | 0.273 | 0.607 | 1 | 0.76 | 0.582 | 0.988 | 0.04a |
rs28897670 | TIMP4 | 12156160 | G/A | 0.094 | 0.115 | 0.726 | 1 | 0.80 | 0.553 | 1.167 | 0.25 |
rs2279750 | TIMP4 | 12157117 | C/A | 0.218 | 0.279 | 1 | 0.888 | 0.72 | 0.55 | 0.936 | 0.01a |
rs3755724 | TIMP4 | 12159406 | C/T | 0.404 | 0.464 | 0.806 | 0.494 | 0.78 | 0.621 | 0.985 | 0.04a |
Notes.
Minor allele.