Fig. 1.
Concentration-response relation (a) of isolated perfused lungs from normoxic and hypoxic rats (n = 6/group) to the BKCa channel activator, NS1619 (vehicle). Graphical representation (b) of the resultant percent vasorelaxation in response to NS1619 ([30μM]) in normoxic and hypoxic lungs. Concentration-response relation (c) of isolated perfused lungs from normoxic and hypoxic rats (n = 4/group) to the exogenous NO-donor, sodium nitroprusside (SNP). Values are means ± SE. *P < 0.05 vs. normoxia