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. Author manuscript; available in PMC: 2019 Jan 27.
Published in final edited form as: J Am Chem Soc. 2018 Sep 21;140(39):12622–12633. doi: 10.1021/jacs.8b08436

Figure 7.

Figure 7

19F label of nucleoside 1 serves as a useful tool to determine the GQ structure of H-Telo overhang in cellular environment. (a) 19F and 1H NMR spectra of ON 8 in intraoocyte buffer, oocyte clear lysate, egg extract, and intraoocyte buffer containing 40% PEG. (b) 19F and 1H NMR spectra of ON 9 in intraoocyte buffer, oocyte clear lysate, egg extract, live oocytes, and intraoocyte buffer containing 40% PEG. NMR measurements were performed at 18 °C.