Table 1.
Patient demographic and clinical characteristics
| Variable | Primary Analysis (All Patients) | Secondary Analysis (Survivors) | ||||
|---|---|---|---|---|---|---|
| Baseline | Ql | P | Baseline | Ql | P | |
| Total sample size | 52 | 62 | - | 43 | 48 | - |
| Male (n / %) | 37 / 71.2 | 44 / 71.0 | 0.98 | 33 / 76.7 | 34 / 70.8 | 0.52 |
| Age, years (mean, SD) | 56.5, 14.9 | 59.1, 16.5 | 0.40 | 56.5, 14.3 | 56.6, 13.8 | 0.96 |
| First AM-PAC t-score (median [IQR]) | 23.6 [23.6, 29.6] | 23.6 [23.6, 28.6] | 0.33 | 23.6 [23.6, 30.6] | 23.6 [23.6, 28.6] | 0.42 |
| APACHE II score (mean, SD) | 19.7, 7.3 | 18.3, 5.2 | 0.26 | 18.7, 6.6 | 17.5, 5.3 | 0.32 |
| Charlson comorbidity index (median [IQR]) | 5 [3, 7] | 1 [0, 4] | <0.01 | 5 [3, 7] | 1 [0, 3] | <0.01 |
| BMI, kg/m2 (mean,SD) | 29.1, 6.4 | 31.0, 7.6 | 0.15 | 29.1, 5.8 | 31.2, 8.3 | 0.17 |
| MS-DRG weight (median [IQR]) | 13.1 [7.7, 25.4] | 15.3 [7.4, 26.2] | 0.26 | 9.5 [7.7, 25.4] | 16.2 [7.4, 26.2] | 0.20 |
| Markers of critical illness (n / %) | ||||||
| Mechanical ventilator >24 hours | 46 / 88.5 | 56 / 90.3 | 0.75 | 37 / 86.1 | 43 / 89.6 | 0.61 |
| Hours on mechanical ventilator (median [IQR]) | 175.4 [72.2, 317.7] | 153.0 [63.5, 299.5] | 0.59 | 111.2 [65.2, 215.6] | 110.0 [47.9, 205.3] | 0.43 |
| MCS* for any time | 30 / 57.7 | 26 / 41.9 | 0.09 | 25 / 58.1 | 19 / 39.6 | 0.08 |
| CRRT for anytime | 10 / 19.2 | 22 / 35.5 | 0.05 | 6 / 14.0 | 12 / 25.0 | 0.19 |
*
Includes ECMO or temporary VAD