Figure 3. Th17CD39+ cells from AILD patients display a less activated profile and contain lower proportions of FOXP3+ and IL-10+ lymphocytes.
(A) Mean+SEM frequency of Th17CD39+ cells expressing CD69, CD44, CD25, CD161 and FOXP3 in AILD (n=34) and HS (n=16). (B) Mean+SEM frequency of IFNγ, TNF-α, IL-10 and TGF-β producing CD39+ Th17 cells in AILD (n=34) and HS (n=16). *: P≤0.05; **: P≤0.01; ***: P≤0.001. (C) Inverse correlation between frequency of TGF-β producing Th17CD39+ cells and levels of AST, GGT and IgG.