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. Author manuscript; available in PMC: 2019 Jan 27.
Published in final edited form as: J Autoimmun. 2016 May 20;72:102–112. doi: 10.1016/j.jaut.2016.05.005

Figure 4. Th17CD39+ cells from AILD patients display lower levels of ectoenzymatic activity.

Figure 4.

(A) Mean+SEM frequency of CD73+ cells within Th17CD39+ cells in AILD (n=34) and HS (n=16). (B) CD39 ADPase enzymatic activity was assessed by TLC following incubation of Th17 cells with [14C] radiolabeled ADP substrates at different time points. Results from 2 representative AILD patients and 2 representative HS are shown. (C) Mean+SEM AMP and adenosine pixel intensity in AILD (n=4) and HS (n=4). *: P≤0.05; **: P≤0.01; ***: P≤0.001.