Table 1.
Demographic and laboratory data
Number of subjects | Sex (F/M): |
Age (years): |
AST (nv<50IU/1) |
GGT (nv<55IU/1) |
Bilirubin (nv<20μmo1/1) |
IgG (nv 6.5–17g/1) |
Autoantibody Titer* | |||
---|---|---|---|---|---|---|---|---|---|---|
ANA | SMA | LKM-1 | ||||||||
AILD | 38 | 17/21 | 0.1–34.1 (15.2) |
|||||||
Active patients† | 12 | 5/7 | 3.6–30.2 (14.6) |
55–2462 (100) |
143 (27–883) |
12–257 (31) |
8.5–44.3 (19.1) |
0–160 (20) |
0–1280 (10) |
neg |
Remission patients | 26 | 12/14 | 0.1–34.1 (15.6) |
11–49 (23)¶ |
7–223 (17.5)∞ |
3–26 (9)§ |
6.4–29.9 (12.6)‡ |
0–20 (0) |
0–80 (0) |
neg |
Data presented as range (median) unless noted otherwise; nv: normal value
AILD: autoimmune liver disease
: including five patients at disease presentation
AST: aspartate aminotransferase
GGT: gamma glutamyl transferase
IgG: immunoglobulin G
: Autoantibody titer shown as reciprocal
ANA: anti-nuclear antibody
SMA: smooth muscle antibody
LKM-1: liver kidney microsomal antibody type 1
P=0.006,
P=0.009,
P<0.001,
P=0.01 when comparing AST, GGT, bilirubin and IgG levels between patients with active disease and at remission