Table 4.
Prevalence of clinical and laboratory features found in 41 LIG4 deficiency patients.
| Female | 28/41 | 68% |
| Microcephaly | 32/40 | 80% |
| Dysmorphic facial features | 15/41 | 37% |
| Growth failure | 28/40 | 70% |
| Syndactyly/Polysindactyly | 4/41 | 10% |
| Other malformations | 3/41 | 7% |
| Congenital hip dysplasia | 4/41 | 10% |
| Infections (any) | 28/41 | 68% |
| Sinopulmonary infections | 23/41 | 56% |
| Skin conditions | 8/41 | 20% |
| Warts | 2/41 | 5% |
| Hypogammaglobulinemia | 25/30 | 83% |
| Very low CD19+ B-cells | 24/30 | 80% |
| Malignancy | 10/41 | 24% |
| Bone marrow failure | 17/39 | 44% |
| Radiosensitivity | 24/28 | 86% |
(100% radiosensitivity with ionizing radiation).