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. 2019 Jan 21;9:1877. doi: 10.3389/fphys.2018.01877

Table 7.

Model performance for different cutoff points of the predicted probabilities for combined TREC and KREC with regards o all lymphocyte subpopulations measured.

Cutoff (probability) (probability) PPV (%) NPV (%) Sensitivity (%) Specificity (%) Youden index
0.3 43 85 93 24 17.3
0.35 48 71 61 59 20.2
0.4 52 68 43 75 18.2
0.45 54 66 28 86 13
0.55 65 64 13 96 8.5

Optimum cut-off point based on maximum value of the J index is presented in bold.