Table 2.
Pulmonary hemodynamics and ventricular physiological responses to inhaled iloprost.
| Variables | IPAH | P value | CTD-PAH | P value | CHD-PAH | P value | |||
|---|---|---|---|---|---|---|---|---|---|
| Before | After | Before | After | Before | After | ||||
| mPAP, mmHg | 58 ± 13 | 52 ± 15 | <0.01 | 48 ± 13 | 41 ± 11 | <0.01 | 63 ± 21 | 55 ± 16 | 0.002 |
| PVR, Wood U | 14.2 (6.8, 18.4) | 9.2 (5.6, 15.2) | <0.01 | 11.1 (7.8, 15.2) | 8.1 (5.1, 11.3) | <0.01 | 16.9 (7.9, 21.2) | 11.7 (5.4, 16.0) | 0.02 |
| RVEDV, ml | 187 ± 45 | 178 ± 46 | <0.01 | 154 (118, 191) | 141 (109, 199) | 0.001 | 227 ± 114 | 217 ± 113 | 0.005 |
| RVESV, ml | 137 ± 42 | 123 ± 43 | <0.01 | 98 (67, 135) | 92 (63, 125) | <0.01 | 161 ± 101 | 144 ± 97 | <0.01 |
| RVSV, ml | 50 ± 18 | 55 ± 20 | <0.01 | 55 (43, 61) | 56 (45, 67) | 0.002 | 66 ± 23 | 74 ± 26 | 0.001 |
| RVEF, % | 27 ± 10 | 31 ± 12 | <0.01 | 35 ± 11 | 38 ± 11 | <0.01 | 34 ± 16 | 39 ± 17 | <0.01 |
| LVEF, % | 59 (55, 62) | 62 (55, 67) | 0.002 | 67 (57, 76) | 66 (60, 77) | 0.056 | 56 ± 14 | 59 ± 14 | 0.01 |
mPAP, mean pulmonary artery pressure; PVR, pulmonary vascular resistance; RV, right ventricle; LV, left ventricle; EDV, end-diastolic volume; ESV, end-systolic volume; EF, ejection fraction; SV, stroke volume.