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. 2019 Jan 3;11:425–439. doi: 10.1016/j.isci.2018.12.033

Figure 3.

Figure 3

Exercise Increases Mitochondrial Activity, Glucose Metabolism, and Genes Involved in Fatty Acid Oxidation in ingWAT

(A–D) (A) Expression of genes involved in mitochondrial activity and beiging, (B) glucose metabolism, and (C) fatty acid oxidation. (D) Protein expression of UCP1 in ingWAT. Data are presented as means ± SEM (n = 8/group; *p < 0.05, **p < 0.01, ***p < 0.001).

(E and F) (E) Basal OCR in adipocytes differentiated from sedentary and trained ingWAT and (F) bioenergetic profiles of adipocytes differentiated from sedentary and trained ingWAT. Data are presented as means ± SEM (n = 5/group; ***p < 0.001).

(G–I) (G) Images and (H) quantification of NADH autofluorescence and (I) NADH-positive area in ingWAT. Data are presented as means ± SEM (n = 3/group; *p < 0.05 compared with baseline; #p < 0.05 compared with day 5). Figure 3G: scale bar, 50μm.

(J–L) Protein expression of (J) HK2, (K) GLUT1, and (L) GLUT4 in ingWAT. Data are presented as means ± SEM (n = 8/group; *p < 0.05).

(M–O) (M) Glucose uptake in differentiated adipocytes isolated from sedentary and trained ingWAT. Data are presented as means ± SEM (n = 3/group; **p < 0.01). Protein expression of (N) CD36 and (O) FATP1 in ingWAT. Data are presented as means ± SEM (n = 8/group; **p < 0.01).