Table III.
Levels of tested biomarkers in patients with intrahepatic cholestasis of pregnancy with a history of intrahepatic cholestasis of pregnancy and without a history of intrahepatic cholestasis of pregnancy and the control group
Variable | β-klotho [pg/ml] | FGF-19 [pg/ml] |
---|---|---|
ICP without H/O ICP (n = 14) | 468.84 (463.24) | 54.58 (21.94) |
ICP with H/O ICP (n = 8) | 221.27 (211.68) | 41.84 (25.19) |
Controls (n = 23) | 520.56 (802.70) | 48.20 (38.75) |
P-values | 0.017 | 0.461 |
ICP – intrahepatic cholestasis of pregnancy, H/O ICP – previous history of intrahepatic cholestasis of pregnancy among the multipara. Values are given as the median (interquartile range). Group medians were compared using the Kruskal-Wallis test, followed by the Conover post hoc analysis for the two-group pairwise comparisons.