Figure 1.

Treatment of apoE^–/– mice with PM2.5 induced increased serum pro-inflammatory factor levels but had no significant effects on serum glucose and lipids. ApoE^–/– mice were fed a high-fat, atherogenic diet containing 1.25% cholesterol and 21% fat, and were administered PM2.5 (30 mg/kg/day) for 8 weeks. Serum glucose, TC, TG, LDL-C and HDL-C (A, p = 0.67, 0.6915, 0.9495, 0.5612, 0.7851, respectively), as well as IL-6 and TNF-α (B, C, p = 0.0196, 0.0367) were measured by ELISA

Data represent the mean ± SE (n = 8). *P < 0.05 versus control.