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PM2.5 altered lesion areas and cellular composition in aortic roots of apoE-/- mice. Lesion areas in sections from aortic roots were stained with Masson trichrome (Aa, p = 0.0231). The quantities of macrophages (Ab, p = 0.0183), SMC (Ac, p = 0.6355) and content of collagen (Ad, p = 0.025) in the plaques of aortic roots were determined by immunohistochemistry and Sirius Red staining, respectively
Data represent the means ± SE (n = 8). *P < 0.05 versus control.
