Table 6.
Drug | Mechanism of action | Current phase in clinical trials |
---|---|---|
Ixekizumab | IL-17A inhibitor | SPIRIT-P2 Phase III (NCT02349295) |
Abatacept | CTLA4-Ig | Phase III (NCT01860976) |
Risankizumab | IL-23 inhibitor | Phase II (NCT02986373) |
Guselkumab | IL-23 inhibitor | Phase II (NCT02319759) |
Tofacitinib | Oral JAK inhibitor | Phase III (NCT01976364) |
Tildrakizumab | IL-23 inhibitor | Unknown currently |
CTLA4-Ig: cytotoxic T lymphocyte-associated antigen-4 immunoglobulin fusion protein.