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. Author manuscript; available in PMC: 2019 Jan 28.
Published in final edited form as: Expert Rev Clin Pharmacol. 2017 May 22;10(8):899–910. doi: 10.1080/17512433.2017.1329009

Table 6.

Medications in development for PsA.

Drug Mechanism of action Current phase in clinical trials
Ixekizumab IL-17A inhibitor SPIRIT-P2 Phase III (NCT02349295)
Abatacept CTLA4-Ig Phase III (NCT01860976)
Risankizumab IL-23 inhibitor Phase II (NCT02986373)
Guselkumab IL-23 inhibitor Phase II (NCT02319759)
Tofacitinib Oral JAK inhibitor Phase III (NCT01976364)
Tildrakizumab IL-23 inhibitor Unknown currently

CTLA4-Ig: cytotoxic T lymphocyte-associated antigen-4 immunoglobulin fusion protein.