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Time-dependence of each parameter in the in vitro dry eye model. Figures show results of cell viability (A), related intracellular ROS levels (B), mRNA levels of p53 (C), p21 (D) and p16 (E) after each desiccation time treatment in the in vitro dry eye model. Data are expressed as mean ± SD (n = 3–6). *p<0.05, #p<0.01 vs desiccation treatment at 0 h.
