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. 2018 Dec 4;119(2):1456–1518. doi: 10.1021/acs.chemrev.8b00136

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Copyright © 2018 American Chemical Society

This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.

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(A) Schematic of the lateral flow assay for detection of EBOV glycoprotein. Polymeric particles containing gold nanoparticles (AuNPs) and quantum dots (QDs), which the authors named dual readout nanospheres (RNs), were utilized as labels for signal readout. (B) TEM image of the dual readout nanosphere, showing AuNPs and QDs adsorbed to the polymeric particle. (C) Titration of EBOV glycoprotein, using the visual detection of AuNPs for signal readout. (D) Titration of EBOV glycoprotein, using the fluorescence of the QDs for signal readout. Adapted from ref (257). Copyright 2017 American Chemical Society.