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(A) Principle of the plasmonic ELISA. In positive samples, antibody-conjugated catalase depleted H2O2, causing a shift in SPR and absorbance of AuNPs from red to blue that is proportional to p24 concentration. (B) Naked eye detection of p24. The visual data demonstrated that the assay was specific for p24 versus a control protein (BSA). Adapted with permission from ref (396). Copyright 2012 Springer Nature.
